Rey Mysterio will step back into a WWE ring this weekend at WrestleMania 42 in Las Vegas, returning from a lengthy injury layoff to join a six-man Ladder Match for the WWE Men's Intercontinental Championship. The addition puts Mysterio alongside Penta, JD McDonagh, Je'Von Evans, Dragon Lee and Rusev in one of the event's most dangerous matches.
Mysterio has been out of action for most of 2026 after injuring his arm in a match against Austin Theory on an episode of WWE Raw in February, but he said he is ready to go. “I'm more than 100%,” he said. “I'm excited.”
The return matters because Mysterio is not only coming back to a title match, he is doing it in a format that has defined his career and his body. He has held the Intercontinental Championship on two different occasions, and this weekend he will try to win it again after missing WrestleMania last year when he was hurt a day before the event.
Mysterio called the ladder match “a perfect fit” and said he has not been in that many during his WWE career. “I'm an adrenaline junkie,” he said, adding that his health is “in great shape right now and I'm looking forward to this Saturday.” That confidence carries extra weight because he said he has never returned from injury in a dangerous ladder match before.
He did point to one previous comeback in WCW, when he returned from a torn ACL and wrestled Chris Jericho for the Cruiserweight Title in San Diego. Even so, he made clear that this time is different: “This is a first.”
The match gives WrestleMania 42 a familiar Rey Mysterio storyline — speed, risk and the chance to leave Las Vegas with another championship — while also putting Penta in the center of a high-stakes field that can shift in an instant. For Mysterio, the question is not whether he is ready to climb. It is whether his first ladder-match return from injury becomes the comeback he has been chasing all year.
