Casey Mize — Confirmed: started for the Detroit Tigers in the tigers vs twins Game 10 opener at Target Field, delivering the first pitch at 7:40 p.m. ET against Minnesota starter Joe Ryan. Detroit opened a four-game road series in Minneapolis after a 5-3 loss to the St. Louis Cardinals on Sunday that closed the Tigers' first homestand.
Joe Ryan — Confirmed: started for the Minnesota Twins opposite Casey Mize and entered Game 10 with a 0-1 record and a 4.82 ERA; Casey Mize — Confirmed: entered the game with a 0-0 record and a 1.50 ERA. The pitching matchup established the starters for the series opener and set the tone for the four-game slate that counts toward early- season rotation workloads.
Detroit Tigers — Confirmed: began the 4-game road series at Target Field in Minneapolis, Minnesota, on Monday at 7:40 p.m. ET, with the game available on Detroit SportsNet, MLB.TV and the Tigers Radio Network. The Tigers arrived in Minnesota after a 5-3 defeat at home on 2026-04-05 that left Detroit 4-5 after nine games.
Cleveland Guardians — Confirmed: led the American League Central at 6-4 after 10 games; Detroit Tigers, Chicago White Sox and Kansas City Royals — Confirmed: were each 4-5 after nine games; Minnesota Twins — Confirmed: were 3-6 after nine games. The standings place the Monday opener squarely into an early division race where each series swing can affect positioning.
Casey Mize — Confirmed: took the mound for Game 10 and now embodies the immediate human element of Detroit's early-season push; his start followed a team loss that left the Tigers level with two other American League Central clubs at 4-5, while the Guardians sit at 6-4. Fans and roster watchers should note that Mize's 1.50 ERA entering the game and Joe Ryan's 4.82 ERA frame how the teams approached matchup decisions for the four-game series and the distribution of innings across upcoming starts.