Kris Jenner said on Tuesday’s episode of the She MD podcast that she tried Ozempic once, then got so sick and nauseous that she could not work. The 70-year-old reality star said the GLP-1 drug quickly made her feel “really sick,” forcing her to call Dr. Thais Aliabadi for help.
“We tried it once when no one knew what it was,” Jenner said, adding, “I can’t work anymore. I can’t, I’m so sick. I can’t like—nauseous.” She said she and Aliabadi then decided to switch to peptide injections and supplements instead, a move Jenner called a “game-changer.”
Jenner said the new routine bought her “an extra couple hours at night,” and that she now gets her blood drawn every three months to keep her hormones balanced. Her account landed after months of speculation over whether she had used Ozempic, a drug typically prescribed for weight management and Type 2 diabetes, where nausea and gastrointestinal discomfort are among the most commonly reported side effects for GLP-1 users.
The admission also fits a pattern Jenner has already discussed publicly: she has said she had a facelift about 15 years ago, and another facelift that drew widespread attention earlier last year. But on Tuesday, she answered the question that had been hanging over the speculation, saying she did try Ozempic — and that the experience ended because she could not tolerate how sick it made her feel.
What she described was not a transformation story so much as a stop-and-start adjustment, with the drug abandoned after one try and replaced by a different regimen she said she could actually live with. For Jenner, the Ozempic experience was not the headline; the inability to function was.